Description: Understanding cancer metabolism is essential for developing new therapies to improve patient outcomes. This course explores the intricate metabolic and biosynthetic pathways in cancer cells, and delves into how cancer cells reprogram their metabolism to support rapid, uncontrolled growth. We also discuss new emerging strategies to exploit metabolic vulnerabilities in cancer.
Structure: Each class will begin with a short lecture, followed by 2 student-led journal club-style presentations on recent cutting-edge papers in the field.
Outcome: At the end of this course, each student will have a strong understanding of the metabolic networks that cancer cells rely on to survive and grow. Students will become familiar with the exciting scientific discoveries that have shaped the field in recent years, and learn how the unique metabolism of cancer cells can be exploited for therapeutic benefit.
Grading: Grading will be based on 1) student presentations and 2) participation in class discussions.
Course Materials: No materials required ahead of time. Published papers will be provided for discussion.