• Course Code: 16:695:621
  • Credits: 1
  • First Year Curriculum: yes
  • Subsequent Year Curriculum: Biochemistry, Cell and Developmental Biology, Cellular & Molecular Pharmacology, Microbiology & Molecular Genetics, Physiology and Integrative Biology
  • Instructor: De, Subhajyoti
  • Semester/Year: Spring 2025
  • Semester(s) Offered: Spring

Description: Next generation sequencing (NGS) technologies allow us to sequence DNA and RNA quickly and cheaply than that was previously possible, revolutionizing the study of genomics and molecular biology, ultimately guiding clinical decision making in Precision Medicine.  The mini-course will comprise of 6 instructed sessions and one hands-on tutorial session, and a mini-essay will be due in the last session. In an instructional session, first I will give an overview of the topic, guided by a classic review paper. Then, one (or two depending on the class strength) student(s) will present a research paper engaging the class in a scholarly group discussion. The students will learn about the emerging applications of the next generation sequencing technologies, best practice guidelines, key considerations during design of experiments, and interpretation of results.