Description: CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) gene editing technology has revolutionized many biomedical research fields. The one-month, 8-session mini-course will cover the most important gene editing approaches by CRISPR technology and provide example applications of each gene editing modality. Students will get oriented in this exciting but highly complex field, learn the CRISPR methodologies currently used in the literature, become familiar with the various CRISPR approaches and tools, and learn to choose the right CRISPR gene editing tools for their research.
Structure: The course director will give an overview lecture on CRISPR biology and CRISPR technologies in the first session. 7 “classic” research articles in CRISPR technology field will be assigned by the course director to students. These research articles will be presented and discussed in the following sessions. At the end of the course, there is a take-home exam to help students learn the take-home messages of the course. The take-home exam includes two to three questions on choosing the correct genome editing platform technology for gene therapy for different genetic diseases.
Outcome: Through the lecture, group learning, and take-home exam, the students are expected to understand, learn, and use the various gene editing strategies of CRISPR technology.