Description: Disruption of metabolic homeostasis plays a key role in leading to metabolic disorders. In this course, we examine the molecular and physiological basis of human metabolic diseases, focusing on the liver. Methodologies leading to scientific discoveries and potential preventive and therapeutic agents will also be discussed. Structure: Introductory lectures and student presentations of publications.
Outcome: At the end of this course, students will be able to explain and apply the integrated biochemical pathways that are discussed in lectures as they relate to liver metabolism, in a disease-related context. Students will also be able to apply their knowledge in participatory in-class “Journal Club” type assessments of published papers.