Course Descriptions

Description: Model systems have provided information about aspects of human cancer not available directly from humans. Models include viruses, bacteria, yeast, cell lines, organoids, worms, flys, fish, mice, microfluidic systems, mathematical, and computational models, etc. The information includes molecular and cellular aspects about tumor initiation, progression, evolution, invasion, metastasis, prevention, and therapy. The instructor will introduce unmet challenges of human cancer, and a survey of model systems, with references to published review articles. Each student will select any model system that has been used to illuminate a cancer problem. Each student will make a presentation reviewing experimental articles about the selected model system, lead a discussion, and write a two-page letter of intent arguing for the use of their selected model system to illuminate a particular cancer problem.