My group integrates structural approaches, in particular single-particle cryo-electron microscopy (cryo-EM), cryo-electron tomography (cryo-ET), correlative light and electron microscopy (CLEM), single-molecule methods, and novel artificial intelligence (AI) algorithms to study large macromolecular assemblies with medical relevance. By using these methods, we expect to reveal mechanistic information that may subsequently facilitate development of novel therapeutics for the treatment of cancer and neurological disorders.
Program Faculty
- Arek Kulczyk
- Assistant Professor
- Department: Department of Biochemistry and Microbiology
- Graduate Program(s): Biochemistry
- Major Research Interest(s): Cancer Biology, Computational Biology, DNA replication and repair, Drug Discovery, Structural Biology
- Research Techniques: Atomic or Electron microscopy, Biochemistry, Bioinformatics / Computational, Biophysics, Protein Structure / Crystallography
- Research Organism(s): Bacteria, Cell lines, in silico, in vitro, Viruses
- Rotation Faculty
- Phone: 1.8484454553
- Email: arek.kulczyk@rutgers.edu
- School of Environmental and Biological Sciences
- Institute for Quantitative Biomedicine
- Center for Integrative Proteomics Research CIPR, Room 208H
- 174 Frelinghuysen Road
- Piscataway, NJ 08854-8076
- Key Words: Structural Biology, Bioinformatics, Artificial Intelligence (AI), Cancer, Neurological Disorders, DNA replication, DNA repair, Basement Membranes, Cryo-Electron Microscopy (cryo-EM), Cryo-Electron Tomography (cryo-ET), Correlative Light and Electron Microscopy (CLEM), Single-Molecule Methods, Fluorescent Microscopy, Structure Determination, Drug Development
- Lab Site URL
