The central focus of my lab has been on understanding the metabolic and signaling role of retinoids (vitamin A and its metabolites) that act as transcriptional regulators of genes controlling cellular proliferation, differentiation, metabolism, and apoptosis. Specifically, my research is directed toward understanding the molecular and cellular mechanisms of how retinoids, as well as retinoid-interacting proteins, are involved in maintaining the physiological functions of hepatic, adipose, pulmonary, and intestinal cells in the context of whole-body metabolism. My lab is interested in understanding how the disruption of retinoid metabolism and signaling contributes to the development of functional alterations in the adult lungs as well as in metabolic disease, including obesity, diabetes, and fatty liver disease.
Program Faculty
- Igor Shmarakov
- Assistant Professor
- Department: Department of Animal Sciences
- Graduate Program(s): Biochemistry | Physiology and Integrative Biology
- Major Research Interest(s): Immunology, Metabolism / Nutrition, Organelle biology, Pathogenesis, Signaling
- Research Techniques: Biochemistry, Bioinformatics / Computational, Cell Biology, Cell culture, Single Cell RNA Techniques
- Research Organism(s): Cell lines, Humans, in vitro, Mice
- Rotation Faculty
- Phone: 1.8489325617
- Email:
This email address is being protected from spambots. You need JavaScript enabled to view it. - School of Environmental and Biological Sciences
- Foran Hall, Room 326
- 59 Dudley Road
- New Brunswick, NJ 08901
- Key Words: Retinoids, Lipids, Metabolism, Inflammation, Acute Lung Injury
- Lab Site URL