The human brain contains about 100 billion neurons wired into complex circuits through hundreds of trillions of synapses. The development and plasticity of these synapses are essential for our ability to learn, remember and can even affect our personality. Our laboratory is interested in the cellular and molecular basis of synaptic plasticity, and how it translates to learning and memory processes. In addition, we are interested in how memory fails in pathological processes like Alzheimer's disease. Specifically, we are focusing on the roles of a group of cell polarity regulators that have been genetically implicated in various neurological disorders, including autism, schizophrenia, and Alzheimer's disease.
Program Faculty
- Huaye Zhang
- Professor
- Department: Department of Neuroscience and Cell Biology
- Graduate Program(s): Cell and Developmental Biology | Cellular and Molecular Pharmacology
- Major Research Interest(s): Learning / memory, Neurological disease, Neuroscience, Signaling
- Research Techniques: Biochemistry, Cell Biology, Cell culture, Fluorescent and super resolution microscopy, Genetic engineering
- Research Organism(s): Cell lines, Mice
- Phone: 1.7322353433
- Email:
This email address is being protected from spambots. You need JavaScript enabled to view it. - Robert Wood Johnson Medical School
- RWJMS Research Tower, Room 304
- 675 Hoes Lane West
- Piscataway, NJ 08854-8021
- Key Words: cell polarity, dendritic spines, synaptic plasticity, membrane trafficking, cytoskeleton, autism, Alzheimer's disease, learning and memory
- Lab Site URL