The development of metabolic diseases, such as fatty liver, cardiovascular disease, and diabetes is influenced by nutritional, lifestyle, and genetic factors and result in myriad molecular changes that alter the progression of disease. The overarching goal of the Sampath Lab is to delineate the cellular alterations that occur during the development of metabolic diseases. In this way, we seek to identify pathways that can be targeted for nutritional and pharmaceutical therapies to preserve health and improve health outcomes. We are particularly interested in the regulation of systemic metabolic health by dietary and cellular lipids, especially saturated and monounsaturated fatty acids, cellular processing of these lipids, and intra- and inter-organ communication by lipids. Recent studies are focused on intestinal sensing and processing of lipids and regulation of systemic metabolic health by intestine-derived signals, including lipids, enteroendocrine hormones, and the gut microbiome.
Program Faculty
- Harini Sampath
- Associate Professor
- Department: Department of Nutritional Sciences
- Graduate Program(s): Physiology and Integrative Biology
- Major Research Interest(s): Cancer Biology, Immunology, Metabolism / Nutrition
- Research Techniques: Biochemistry, Cell culture, Metabolomics, Single Cell RNA Techniques
- Research Organism(s): Cell lines, Mice
- Rotation Faculty
- Phone: 1.8489320266
- Email:
This email address is being protected from spambots. You need JavaScript enabled to view it. - School of Environmental and Biological Sciences
- Institute for Food Nutrition & Health IFNH, Room 222
- 61 Dudley Road
- New Brunswick, NJ 08901
- Key Words: Lipids, nutrition, diet, cancer, intestinal health
- Lab Site URL