The Barbet laboratory studies the biology of mononuclear phagocytes such as monocytes, dendritic cells and macrophages. At the intracellular level, the laboratory is interested in the calcium homeostasis and how this second messenger is involved in the sensing of the environment of mononuclear phagocytes. The laboratory is investigating the calcium signal in the context of pathogens recognition but also in response to cell death. At mucosal surfaces such in the lungs or the intestines, we are exploring how mononuclear phagocytes orchestrate the immune response to either promote either an efficient adaptive response (including antibody production) or tissue repair.
Program Faculty
- Gaetan Barbet
- Assistant Professor
- Department: Department of Pediatrics
- Graduate Program(s): Cellular and Molecular Pharmacology | Microbiology and Molecular Genetics
- Major Research Interest(s): Immunology, Microbiome, Signaling
- Research Techniques: Biochemistry, Cell Biology, Cell culture, Fluorescent and super resolution microscopy, Imaging
- Research Organism(s): Bacteria, Mice, Viruses
- Phone: 1.7322350608
- Email:
This email address is being protected from spambots. You need JavaScript enabled to view it. - Robert Wood Johnson Medical School
- Child Health Institute of New Jersey CHI, Rm 4274
- 89 French Street
- New Brunswick, NJ 08901-1935
- Key Words: Intestinal immunity, Innate immune pathway, Calcium signaling
- Lab Site URL